Everything You Know About Rifampicin

Rifampicin's a strong, strong antibiotic. It's going to tackle many bacterial infections! Men, you'll get this one as a tablet or through an IV line. You know that! When you've got active TB, you'll take 10 mg for every kilo you weigh each day. Yes, that's the standard! Your max daily dose? It's 600 mg, obviously. Many, many of you take this med for 6 months. It's going to work with other meds. That said, men, you've got to keep your doc up-to-date about all side effects you see!

Men, this antibiotic's a great, great tuberculosis treatment. Obviously, though, you've got other meds for TB out there too. But rifampicin does more! It's a strong endocarditis treatment. Great! It'll even work as a treatment for leprosy. Men, this med's very, very strong. It'll bring you a win! You've just got to understand how it works first.

How It Works

You know what rifampicin is: an antibiotic! Men, this one's a strong, strong antimycobacterial medicine. It's going to tackle bacterial infections like no one's business. This med's going to win for you! It does this by stopping bacteria from completing RNA synthesis, men. This one binds to the beta subunit of what you know as the DNA-dependent RNA polymerase. What a huge, huge win. Men, this is why the RNA transcription stops! Your liver's going to absorb the med. And then? Your body excretes it through your poo!

Men, this med gets to its peak concentration in 2 to 4 hours. Yes! It carries a half-life of 3 to 4 hours. If you've got liver issues? This is longer! End-stage kidney disease means this med's got a half-life of up to 11 hours.